Description
Triptorelin is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH; pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH₂). It binds to the GnRH receptor, initiating Gq/PLC and IP₃–Ca²⁺ signaling cascades that regulate luteinizing and follicle-stimulating hormone release in experimental systems. Triptorelin is used in receptor biology and endocrine regulation research to study hypothalamic–pituitary–gonadal axis modulation.
For research use only. Not for human consumption.
References:
Sandow J et al., Life Sci, 1984 35(15):1503–1513
Conn PM et al., Endocr Rev, 1994 15(6): 682–715
Limonta P et al., J Steroid Biochem Mol Biol, 2003 85(2–5): 249–258


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